{"id":870,"date":"2018-07-30T09:25:53","date_gmt":"2018-07-30T03:55:53","guid":{"rendered":"http:\/\/macsforcancer.com\/blog\/genetic-testing-eliminates-anxiety-about-common-hereditary-cancer\/"},"modified":"2018-07-30T18:41:06","modified_gmt":"2018-07-30T13:11:06","slug":"genetic-testing-eliminates-anxiety-about-common-hereditary-cancer","status":"publish","type":"post","link":"https:\/\/macsforcancer.com\/blog\/genetic-testing-eliminates-anxiety-about-common-hereditary-cancer\/","title":{"rendered":"Genetic Testing Eliminates Anxiety About Common Hereditary Cancers"},"content":{"rendered":"<p>It is estimated that <span style=\"color:rgb(35,31,32);\">5-10% of all cancers are caused by inheritance of genes that are mutated or damaged. I have often seen the children of Cancer patients being worried about they themselves getting cancer. Often the come to me with a irrelevant tests, advised by physicians or otherwise, which would not estimate there risks of getting cancer. Is there a way to understand whether one is at risk? Is there a simple test available?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"color:rgb(0,0,0); font-style:normal; font-variant-ligatures:normal; font-variant-caps:normal; font-weight:400; letter-spacing:normal; orphans:2text-indent:0px; text-transform:none; white-space:normal; widows:2; word-spacing:0px; -webkit-text-stroke-width:0px; text-decoration-style:initial; text-decoration-color:initial; margin:0in0in0.0001pt; font-size:11pt; font-family:Calibri,sans-serif; text-align:left;\"><span style=\"color:rgb(35,31,32);\">In this regard I would like to share a case study of Ruchi (name changed), a 40- year-old chartered accountant. Her paternal grandmother had breast cancer. One of her cousins from her father\u2019s <\/span><span style=\"color:rgb(35,31,32); font-size:11pt;\">side of the family had been diagnosed with throat cancer. She was worried about her own risks for developing cancer. After some deliberation, she decided to consult<\/span> me.<\/p>\n<p class=\"MsoNormal\" style=\"color:rgb(0,0,0); font-style:normal; font-variant-ligatures:normal; font-variant-caps:normal; font-weight:400; letter-spacing:normal; orphans:2text-indent:0px; text-transform:none; white-space:normal; widows:2; word-spacing:0px; -webkit-text-stroke-width:0px; text-decoration-style:initial; text-decoration-color:initial; margin:0in0in0.0001pt; font-size:11pt; font-family:Calibri,sans-serif; text-align:left;\">After understanding<span style=\"color:rgb(35,31,32);\"> Ruchi&#8217;s family history and her concern about inheriting genes that may increase her personal risk of cancer and a genetic counselling. A blood sample was collected for DNA testing. <\/span><\/p>\n<p class=\"MsoNormal\" style=\"color:rgb(0,0,0); font-style:normal; font-variant-ligatures:normal; font-variant-caps:normal; font-weight:400; letter-spacing:normal; orphans:2text-indent:0px; text-transform:none; white-space:normal; widows:2; word-spacing:0px; -webkit-text-stroke-width:0px; text-decoration-style:initial; text-decoration-color:initial; margin:0in0in0.0001pt; font-size:11pt; font-family:Calibri,sans-serif; text-align:left;\"><span style=\"color:rgb(35,31,32);\">In Ruchi\u2019s case, DNA analysis showed that she did not have pathogenic (disease-causing) mutations in any of the genes tested.<span> <\/span><\/span><\/p>\n<p>Hence concluding:<br \/>\na. Ruchi does not have germline mutant (abnormal) copies of the genes tested, in her DNA.<span> <\/span><br \/>\nb. Her risk for developing inherited breast and ovarian cancer is low. However, the risk for developing sporadic (by chance) cancer is still present like rest of the population.<br \/>\nc. Her family history of cancer could also be a result of mutations in other genes or other regions of the tested genes, not covered by the test.<br \/>\nd. Ruchi\u2019s chances of suffering from hereditary cancer are low.<\/p>\n<p class=\"MsoNormal\" style=\"color:rgb(0,0,0); font-style:normal; font-variant-ligatures:normal; font-variant-caps:normal; font-weight:400; letter-spacing:normal; orphans:2text-indent:0px; text-transform:none; white-space:normal; widows:2; word-spacing:0px; -webkit-text-stroke-width:0px; text-decoration-style:initial; text-decoration-color:initial; margin:0in0in0.0001pt; font-size:11pt; font-family:Calibri,sans-serif; text-align:left;\"><span style=\"color:rgb(35,31,32);\">However, a healthy lifestyle and periodic health check-ups would still be advisable for <\/span>her.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hereditary Cancers are seen in a 5-10% of patients. We can prevent cancer by these people even before it starts. <\/p>\n","protected":false},"author":1,"featured_media":869,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false},"categories":[16,21,142,143],"tags":[30,147,145,146,144],"class_list":["post-870","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer-prevention","category-early-detection-of-cancer","category-familial-cancer","category-hereditary-cancer","tag-cancer","tag-cancer-prevention","tag-family","tag-genes","tag-hereditary-cancer","category-16","category-21","category-142","category-143","description-off"],"aioseo_notices":[],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/macsforcancer.com\/blog\/wp-content\/uploads\/2018\/07\/aaeaaqaaaaaaaaoeaaaajdmwmmu1nzk0ltu1ztgtndy2ys1imzuwltcznjlimgzhyjbmyg-1.jpg","_links":{"self":[{"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/posts\/870","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/comments?post=870"}],"version-history":[{"count":2,"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/posts\/870\/revisions"}],"predecessor-version":[{"id":872,"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/posts\/870\/revisions\/872"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/media\/869"}],"wp:attachment":[{"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/media?parent=870"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/categories?post=870"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/macsforcancer.com\/blog\/wp-json\/wp\/v2\/tags?post=870"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}